DETECT-I (testing for bladder cancer)

We are investigating whether a new urine test called UroMark can detect bladder cancer in patients who are being investigated for haematuria (blood in the urine).

UroMark is currently in the development stage and early results indicate that it can detect bladder cancer with a high degree of certainty. The test detects changes in the DNA of cells which are present in urine. Changes in DNA, called mutations or epigenetic alterations, are present in cells collected from a urine sample if cancer is present. We would like to understand if the UroMark test can detect bladder cancer.

DETECT-I is recruiting men and women who have been referred to hospital to have tests because of the finding of either visible or non-visible blood in the urine (haematuria). Everyone who agrees to take part will be receiving the normal investigations for haematuria as well as UroMark test.

Subjects will be asked to provide a urine sample and complete a brief questionnaire. This will end their participation in the study. The urine sample is collected using a special kit which we have developed to allow patients to provide a sample at home then post to us using a stamped addressed envelope.  


Read more about DETECT-I at the Health Research Authority (HRA).