Bladder cancer affects 11,000 individuals in the UK and over 100,000 in Europe every year. For most people, the first sign of bladder cancer is blood in urine which is called haematuria.
Frequently, visible and non-visible haematuria is also present with non-cancer related conditions such as urinary infection. This means that the diagnosis of bladder cancer is often delayed.
Read more about bladder cancer.
The UroMark test is a highly sensitive test for bladder cancer developed by the Kelly:Feber Lab. The test is 'non-invasive' which means that it is
performed on a urine sample and avoids the traditional technique of having to pass an instrument along the urethra (or water pipe) to visualise the interior bladder.
The UroMark test is uses the latest technology to analyse over 150 cancer related changes to DNA of cells present in urine. Our results to date show that UroMark can detect bladder cancer with high certainty and is able to differentiate between bladder cancer and non-cancer conditions such as urinary infection.
The UroMark test is currently in Phase III validation which is a stage before it can be made available for clinical use. The trials are funded by the Medical Research Council and will complete in 2017.
Already a number of clinical studies have been completed and show that the UroMark test detects almost all cancers.
Learn more about current clinical trials.
What does the test involve?
At this time the test is only available in one of our clinical studies. Patients are asked to provide a urine sample. The sample can be provided from home or their doctors surgery and is collected using a specially developed UroMark collection kit which is simply posted to a receiving laboratory for testing.
Who has developed UroMark?
UroMark has been developed by the Kelly:Feber Lab at University College London. Funding for UroMark has been obtained from the UCLH Biomedical research Centre (National Institute for Health Research), The Medical Research Council, Cancer Research UK, The Urology Foundation and The Rosetrees Trust.
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